he came from Pzrzemysl.
I have seen several of your posts in many places on internet, consistently misspeling the name PRZEMYŚL (Polish), PRZEMYSL (anglicized), Перемишль (Ukrainian), or Peremyshl' (Ukrainian with English transliteration). Pzrzemysl does not fit to any of these patterns.
I am searching the family name of Lizon, grandfather Simon(Samuel) Lizon
Surname Lizoń is reasonably popular in Poland; 1480 persons bear this name. They mostly live in the southern belt of Poland. About 1/4 of them live in town and county of Nowy Sącz.
Wife was Mary Smola from Tarnogora ,believe she was born in Czech.
Smola is a Czech and Slovak name. Polish variation is Smoła (L with stroke). It may be also a Jewish Ashkenazi name. There are only 38 persons with surname Smola in Poland. However, there are 1978 persons named Smoła (with L with stroke.) Take a look at this map: these people are concentrated in several SE counties, including Nowy Sącz, Gorlice, Tarnów, Leżask. The top ten counties are listed in right lower corner of the map.
Wife was Mary Smola from Tarnogora ,believe she was born in Czech.
There are two Tarnogóra places in Poland, and none of Tarnogora in Czech Republic or Slovakia.
The first one would be very likely related with someone of Jewish origin:
Village Tarnogóra, Gmina Izbica, Kranystaw County, Lublin Voivodship, Poland
pl.wikipedia.org/wiki/Tarnog%C3%B3ra_(wojew%C3%B3dztwo_lubelskie)
Izbica was exclusively inhabited by Jews, until WW1. A town had no parish church. During WW2 it was a place of martyrdom of many local and foreign Jews, mostly Czech Jews. Many were sent to Belzec, Majdanek and Sobibór from there.
Second choice:
Village Tarnogóra, Gmina Nowa Sarzyna, Leżajsk County, Subcarpathian Voivodship, pl.wikipedia.org/wiki/Tarnog%C3%B3ra_(wojew%C3%B3dztwo_podkarpackie)
Jacob Mohyla and Eva(Kozak) Mohyla from Chotyneic, Western Ukraine.
You misspelled the village name. It is Chotyniec (Polish), Хотинець (Ukrainian), Khotynets' (transliterated from Ukrainian to English).
The exact location:
Chotyniec, Gmina Radymno, Jarosław County, Subcarpathian Voivodhip, SE Poland, right on the border with Ukraine, en.wikipedia.org/wiki/Chotyniec